At the scale of individual cells, the human body is constantly in motion. Every second, millions of cells divide, ...

After an injury, DNA not only alters its activity but also the way it is organized spatially within the cell nucleus.

"The real 'aha' moment came from biochemical experiments and the cryo-EM structure. Hiroshi Nishimasu and his team could actually see the DNA product sitting in the enzyme, and the structure put these ...

In a new Science study, scientists read the family tree buried inside modern genomes and turned up “ghost ancestors” in every population on Earth that no fossil records can account for. But did our ...

Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...

There are plenty of unanswered questions about the origin of life on Earth. But the research community has largely reached consensus that one of the key steps was the emergence of an RNA molecule that ...

In 1869, Swiss scientist Friedrich Miescher isolated a mysterious substance from cell nuclei—an overlooked finding that would later reshape biology and our understanding of life itself. A ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

Human history is rife with contentions about the purity (and superiority) of the bloodlines of one group over another and claims over ancestral homelands. More than a decade of work on ancient human ...

Back in high school chemistry, I remember waiting with my bench partner for crystals to form on our stick in the cup of blue solution. Other groups around us jumped with joy when their crystals formed ...

Leading Manchester United’s academy is no ordinary backroom role. The club’s heritage of developing young talent is unparalleled in English football, so whoever is tasked with running it has ...

Accurate genome duplication is essential for all living cells. In Escherichia coli and most other bacteria, a circular chromosome is replicated bidirectionally at high speed. Two replisomes, assembled ...