The high complexity and diversity of the eukaryotic transcriptome poses significant challenges for the efficient detection of specific transcripts. Conventional targeted RNA-seq methods often require ...

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An overview of where next-generation sequencing is used, from whole-genome variant discovery to clinical liquid biopsy and single-cell transcriptomics.

Low-dose radiation as a preconditioning regimen for dendritic cell vaccines. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This abstract does not include a full text component.

This eBook explores advances in RNA sequencing (RNA-seq), with key content from BioTechniques’ digital hub and Taylor & Francis journals, Biotechnology and Genetic Engineering Reviews, Immunological ...

Legacy sequencing technologies have, undoubtedly, made comprehensive transcriptome analysis possible and are invaluable for the study of human genetics and mechanisms of diseases. However, legacy ...

Genetic variants that cause rare disorders may remain elusive even after expansive testing, such as exome sequencing. The diagnostic yield of genome sequencing, particularly after a negative ...